State accessibility codes and federal standards/safe harbors all contain requirements specifying the distance of the toilet CL from the near side wall, bathing fixture and adjacent vanities. Installing compliant fixtures can be a challenge especially when the required dimension is a fixed 18″. American Standard has recently released the AccessPRO toilet that allows up to 3.5″ of lateral adjustment of toilet to the right or left. At approximately $1,600 it is likely too expensive to be used throughout a project but offers an alternative compliance strategy when faced with roughed-in plumbing that wandered.
You can download a spec sheet here.